WEBVTT 00:00:00.640 --> 00:00:01.680 Welcome to this guide, 00:00:01.680 --> 00:00:06.440 which sets out the correct use of the Hukyndra single-use pre-filled syringe. 00:00:07.120 --> 00:00:11.440 The syringe is made up of three parts: needle, finger grip and plunger. 00:00:12.320 --> 00:00:13.600 Let’s see how it works. 00:00:14.200 --> 00:00:16.560 Hukyndra should be stored in its original packaging 00:00:16.560 --> 00:00:20.720 in a refrigerator at a temperature of 2 to 8°C. 00:00:21.200 --> 00:00:23.280 If needed (whilst travelling, for example), 00:00:23.280 --> 00:00:30.080 you may also store Hukyndra at room temperature - up to 25°C - for up to 14 days. 00:00:30.560 --> 00:00:33.800 First, take Hukyndra out of the refrigerator. 00:00:34.640 --> 00:00:36.640 Remove the syringe from the packaging; 00:00:37.320 --> 00:00:38.880 make sure that the product is in date 00:00:38.880 --> 00:00:41.160 by checking the expiry date on the label 00:00:41.160 --> 00:00:43.280 and verify that the liquid in the syringe 00:00:43.280 --> 00:00:44.960 is clear and colourless. 00:00:46.800 --> 00:00:51.040 Leave the syringe at room temperature for 15 to 30 minutes before injecting. 00:00:52.400 --> 00:00:53.280 Importantly: 00:00:53.640 --> 00:00:55.120 Do not remove the grey needle cover; 00:00:55.120 --> 00:00:56.440 do not warm Hukyndra 00:00:56.440 --> 00:00:58.280 and do not use the pre-filled syringe 00:00:58.280 --> 00:01:00.520 if the liquid inside has been frozen. 00:01:01.440 --> 00:01:05.760 Place everything on a clean surface: the syringe, an alcohol swab, 00:01:05.760 --> 00:01:10.480 a cotton ball or gauze pad and a puncture-resistant sharps disposal container. 00:01:11.840 --> 00:01:14.200 Wash and dry your hands carefully. 00:01:15.160 --> 00:01:17.240 Begin by choosing an injection site. 00:01:17.600 --> 00:01:21.840 The injection site should be at least 3cms away from your previous injection site 00:01:21.840 --> 00:01:24.640 and can be on the front of your thigh or on your abdomen, 00:01:24.640 --> 00:01:27.080 at least 5cms from your navel. 00:01:28.160 --> 00:01:30.680 Wipe clean the injection site with the alcohol swab 00:01:30.680 --> 00:01:32.480 using a circular motion. 00:01:33.560 --> 00:01:34.320 Importantly, 00:01:34.320 --> 00:01:35.920 do not inject through clothes, 00:01:35.920 --> 00:01:38.400 and do not inject into skin that is sore, bruised, 00:01:38.400 --> 00:01:42.720 red, hard, scarred, has stretchmarks, or areas with psoriasis. 00:01:43.920 --> 00:01:45.960 Hold the pre-filled syringe in one hand and, 00:01:45.960 --> 00:01:49.800 with the other hand, gently pull the needle cover straight off and discard it. 00:01:50.360 --> 00:01:55.160 Do not touch the needle with your fingers and do not let it come into contact with anything. 00:01:55.720 --> 00:01:58.640 It’s normal to see a drop of liquid at the end of the needle. 00:01:59.720 --> 00:02:03.680 Hold the body of the pre-filled syringe in one hand between the thumb and index finger, 00:02:03.680 --> 00:02:08.120 like a pencil, being careful not to pull back on the plunger at any time. 00:02:08.680 --> 00:02:13.960 With your other hand, gently pinch the area of cleaned skin at the injection site and hold it firmly. 00:02:14.920 --> 00:02:20.320 Now insert the needle into the skin at a 45° angle using a quick, dart-like motion. 00:02:21.080 --> 00:02:23.480 Once the needle is in, let go of the skin. 00:02:24.520 --> 00:02:28.520 Slowly push the plunger all the way in until all of the liquid has been injected 00:02:28.520 --> 00:02:30.720 and the pre-filled syringe is empty. 00:02:31.960 --> 00:02:34.720 Lift your finger from the plunger and let it move up slowly, 00:02:34.720 --> 00:02:37.680 retracting from the site into the needle guard. 00:02:37.880 --> 00:02:41.800 Please note that the needle will not retract unless all the liquid has been injected. 00:02:41.800 --> 00:02:45.600 Speak to your healthcare provider if you think you have not had a full dose. 00:02:45.880 --> 00:02:49.960 It’s normal to see a spring around the plunger rod after the needle has retracted. 00:02:50.440 --> 00:02:51.840 After completing the injection, 00:02:51.840 --> 00:02:56.240 place a cotton ball or gauze pad on the skin at the injection site without rubbing. 00:02:56.520 --> 00:02:59.200 Slight bleeding at the injection site is normal. 00:03:00.200 --> 00:03:02.200 Put the used needles, syringes, and sharps 00:03:02.200 --> 00:03:05.520 into a sharps disposal container straight away after use. 00:03:06.960 --> 00:03:08.720 The needle cover, alcohol swab, 00:03:08.720 --> 00:03:10.760 cotton ball or gauze pad and packaging 00:03:10.760 --> 00:03:13.000 may be placed in your household rubbish.