WEBVTT

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Welcome to this guide,

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which sets out the correct
use of the Hukyndra pre-filled pen.

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The pen is made up of four parts:
grey body grip area, inspection window,

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orange needle sleeve
(with the needle inside) and clear cap.

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Let’s see how it works.

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Hukyndra should be stored in its original
packaging in a refrigerator

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at a temperature of 2 to 8°C.

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When needed
(for example when you are travelling),

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a single Hukyndra pre-filled pen
may be stored at 20°C to 25°C

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for a maximum period of up to 30 days

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– be sure to protect it from light.

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First, take Hukyndra out of the refrigerator.

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Remove the pen from the packaging;

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make sure that the product is in date
by checking the expiry date on the label.

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Leave the pen at room temperature for
15 to 30 minutes before injecting.

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Importantly,

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do not remove the clear cap,

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do not warm Hukyndra,

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and do not use the pre-filled pen

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if the liquid inside has been frozen or thawed.

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Place everything on a clean surface:

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the pen, an alcohol swab, a cotton ball
or gauze pad

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and a puncture-resistant sharps
disposal container.

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Wash and dry your hands carefully.

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Begin by choosing an injection site.

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The injection site should be at least 3cms
away from your previous injection site

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and can be on the front of
your thigh or on your abdomen,

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at least 5cms from your navel.

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Wipe clean the injection
site with the alcohol swab

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using a circular motion.

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Importantly,

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do not inject through clothes,

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and do not inject into skin that is sore,

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bruised, red, hard, scarred,

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has stretchmarks, or areas with psoriasis.

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Hold the Hukyndra pen with
the grey body grip area facing upwards.

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Check the inspection window to make sure
that the liquid is clear and colourless.

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It’s normal to see bubbles
in the inspection window.

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Importantly,

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do not use the pen

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if the liquid appears cloudy or contains particles,

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or if the pen has been dropped or crushed.

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Pull the clear cap straight off and discard it.

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Turn the Hukyndra pen
so that the orange needle sleeve

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is pointing towards the injection site.

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Do not put the clear cap back on the pen!

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It's normal to see a few drops of liquid

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come out of the needle.

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Gently pinch the area of cleaned skin
at the injection site to make a raised area,

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and hold it firmly.

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Now place the orange needle sleeve
directly onto the injection site at a 90° angle,

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keeping the inspection window visible.

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Hold the pen in place
against the injection site.

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An initial click will signal the start
of the injection,

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which may take up to 10 seconds to complete.

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Keep the pen in position

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until the orange indicator has stopped moving

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and you may hear a second click.

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Take care to maintain pressure on the injection site

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until you have confirmed the injection is complete.

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Once the injection is complete,
remove the Hukyndra pen from the skin slowly.

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The orange needle sleeve will
cover the needle tip.

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Place a cotton ball or gauze pad on the skin
at the injection site without rubbing.

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Slight bleeding at the injection site is normal.

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Contact your healthcare provider

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if there are more than a few drops of liquid

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at the injection site.

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Put the used needles, pen, and sharps

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into a sharps disposal container
straight away after use.

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The clear cap, alcohol swab,

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cotton ball or gauze pad and packaging

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may be placed in your household rubbish.