WEBVTT 00:00:00.000 --> 00:00:02.160 Welcome to this guide, 00:00:02.160 --> 00:00:06.440 which sets out the correct use of the Hukyndra single-use pre-filled syringe. 00:00:07.120 --> 00:00:11.440 The syringe is made up of three parts: needle, finger grip and plunger. 00:00:12.320 --> 00:00:13.600 Let’s see how it works. 00:00:14.200 --> 00:00:16.560 Hukyndra should be stored in its original packaging 00:00:16.560 --> 00:00:20.240 in a refrigerator at a temperature of 2 to 8°C. 00:00:20.240 --> 00:00:22.640 When needed (for example when you are travelling), 00:00:22.640 --> 00:00:28.240 a single Hukyndra pre-filled syringe may be stored at 20°C to 25°C 00:00:28.240 --> 00:00:30.840 for a maximum period of up to 30 days 00:00:30.840 --> 00:00:32.760 – be sure to protect it from light. 00:00:32.760 --> 00:00:36.000 First, take Hukyndra out of the refrigerator. 00:00:36.840 --> 00:00:38.840 Remove the syringe from the packaging; 00:00:39.520 --> 00:00:41.080 make sure that the product is in date 00:00:41.080 --> 00:00:43.360 by checking the expiry date on the label 00:00:43.360 --> 00:00:45.480 and verify that the liquid in the syringe 00:00:45.480 --> 00:00:47.160 is clear and colourless. 00:00:49.000 --> 00:00:53.240 Leave the syringe at room temperature for 15 to 30 minutes before injecting. 00:00:54.600 --> 00:00:55.480 Importantly, 00:00:55.840 --> 00:00:57.320 do not remove the grey needle cover, 00:00:57.320 --> 00:00:58.640 do not warm Hukyndra 00:00:58.640 --> 00:01:00.480 and do not use the pre-filled syringe 00:01:00.480 --> 00:01:02.720 if the liquid inside has been frozen. 00:01:03.640 --> 00:01:07.960 Place everything on a clean surface: the syringe, an alcohol swab, 00:01:07.960 --> 00:01:12.680 a cotton ball or gauze pad and a puncture-resistant sharps disposal container. 00:01:14.040 --> 00:01:16.400 Wash and dry your hands carefully. 00:01:17.360 --> 00:01:19.440 Begin by choosing an injection site. 00:01:19.800 --> 00:01:24.040 The injection site should be at least 3cms away from your previous injection site 00:01:24.040 --> 00:01:26.840 and can be on the front of your thigh or on your abdomen, 00:01:26.840 --> 00:01:29.280 at least 5cms from your navel. 00:01:30.360 --> 00:01:32.880 Wipe clean the injection site with the alcohol swab 00:01:32.880 --> 00:01:34.680 using a circular motion. 00:01:35.760 --> 00:01:36.520 Importantly, 00:01:36.520 --> 00:01:38.120 do not inject through clothes, 00:01:38.120 --> 00:01:40.600 and do not inject into skin that is sore, bruised, 00:01:40.600 --> 00:01:44.920 red, hard, scarred, has stretchmarks, or areas with psoriasis. 00:01:46.120 --> 00:01:48.160 Hold the pre-filled syringe in one hand and, 00:01:48.160 --> 00:01:52.000 with the other hand, gently pull the needle cover straight off and discard it. 00:01:52.560 --> 00:01:57.360 Do not touch the needle with your fingers and do not let it come into contact with anything. 00:01:57.920 --> 00:02:00.840 It’s normal to see a drop of liquid at the end of the needle. 00:02:01.920 --> 00:02:05.880 Hold the body of the pre-filled syringe in one hand between the thumb and index finger, 00:02:05.880 --> 00:02:10.320 like a pencil, being careful not to pull back on the plunger at any time. 00:02:10.880 --> 00:02:16.160 With your other hand, gently pinch the area of cleaned skin at the injection site and hold it firmly. 00:02:17.120 --> 00:02:22.520 Now insert the needle into the skin at a 45° angle using a quick, dart-like motion. 00:02:23.280 --> 00:02:25.680 Once the needle is in, let go of the skin. 00:02:26.720 --> 00:02:30.720 Slowly push the plunger all the way in until all of the liquid has been injected 00:02:30.720 --> 00:02:32.920 and the pre-filled syringe is empty. 00:02:34.160 --> 00:02:36.920 Lift your finger from the plunger and let it move up slowly, 00:02:36.920 --> 00:02:39.880 retracting from the site into the needle guard. 00:02:40.080 --> 00:02:44.000 Please note that the needle will not retract unless all the liquid has been injected. 00:02:44.000 --> 00:02:47.800 Speak to your healthcare provider if you think you have not had a full dose. 00:02:48.080 --> 00:02:52.160 It’s normal to see a spring around the plunger rod after the needle has retracted. 00:02:52.640 --> 00:02:54.040 After completing the injection, 00:02:54.040 --> 00:02:58.440 place a cotton ball or gauze pad on the skin at the injection site without rubbing. 00:02:58.720 --> 00:03:01.400 Slight bleeding at the injection site is normal. 00:03:02.400 --> 00:03:04.400 Put the used needles, syringes, and sharps 00:03:04.400 --> 00:03:07.720 into a sharps disposal container straight away after use. 00:03:09.160 --> 00:03:10.920 The needle cover, alcohol swab, 00:03:10.920 --> 00:03:12.960 cotton ball or gauze pad and packaging 00:03:12.960 --> 00:03:15.200 may be placed in your household rubbish.